Articular Cartilage Regeneration Using Cell Sheet Technology
نویسندگان
چکیده
منابع مشابه
Articular cartilage regeneration using cell sheet technology.
Cartilage damage is typically treated by chondrocyte transplantation, mosaicplasty, or microfracture. Recent advances in tissue engineering have prompted research on techniques to repair articular cartilage damage using a variety of transplanted cells. We studied the repair and regeneration of cartilage damage using layered chondrocyte sheets prepared in a temperature-responsive culture dish. W...
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Advanced cell-based therapies are promising approaches for stimulating full regeneration of cartilage lesions. In addition to a few commercially available medicinal products, several clinical and preclinical studies are ongoing worldwide. In preclinical settings, high-quality cartilage tissue has been produced using combination strategies involving stem or progenitor cells, biomaterials, and bi...
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INTRODUCTION Cartilage is one of the most important bodily components in allowing one to walk painlessly. It is the connective tissue in your joints, providing smooth articulations and minimalizing friction between bones. Injuries to this tissue are very common and can be detrimental if not treated, due to its lack of intrinsic healing ability. There exist various known causes of cartilage inju...
متن کاملMesenchymal Stem Cell Purification from the Articular Cartilage Cell Culture
Objective Articular cartilage as an avascular skeletal tissue possesses limited capacity to heal. On the other hand, it is believed that the regeneration capacity of each tissue is largely related to its stem cell contents. Little is known about the presence of mesenchymal stem cells in articular cartilage tissue. This subject is investigated in the present study. Materials and Methods Artic...
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Articular cartilage is a highly specialized tissue, that when critically injured has an extremely limited capacity for regeneration. Accordingly, a clinically acceptable treatment option without risks and recurrence is currently unavailable. Inadequately treated destructive and degenerative cartilage injuries will often develop into progressive joint degeneration or osteoarthritis. Conventional...
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ژورنال
عنوان ژورنال: The Anatomical Record
سال: 2013
ISSN: 1932-8486
DOI: 10.1002/ar.22829